Health Systems Action

April 2024

Fatty liver has a new name and a new drug

If you’ve never heard of NAFLD (Non-alcoholic Fatty Liver Disease), or MASLD (Metabolic dysfunction-Associated Steatotic Liver disease (MASLD), its equally non-catchy new name[1], you’re not alone. Yet this condition affects 30% of the global population.   Image: DALL-e As an anesthesiologist working in the operating rooms of a large university medical center in Cleveland, Ohio …

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Polygenic risk scores for Africa?

Despite the huge excitement that greeted the sequencing of the first human genome at the turn of the century, genetic testing isn’t routine. When will this change? Historically, genetic testing was reserved for patients with known or suspected genetic disorders. Tests could identify single gene (“monogenic”) changes linked to conditions like sickle cell disease, haemophilia …

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